Role of eicosanoid in cardiovascular disease

Keywords: Arrhythmias, Atherosclerosis, Cardiovascular disease, Diet, . Dietary factors play a significant role in the development of atherosclerosis. Alteration of the eicosanoid profile may have important effects on inflammation (30) 20 Nov 2011 PUFA play an important role in the composition of all cell membranes where they maintain homeostasis for correct Also shown are their respective eicosanoid derivatives. .. Cardiovascular Disease and Atherosclerosis

8 Nov 2011 The supporting agencies had no role in the design of the study nuclear receptors and transcription factors, changes in eicosanoid profiles, and We reviewed the current evidence for cardiovascular disease (CVD) effects

3.2 Role in inflammation 3.3 Action of prostanoids 3.4 Action of leukotrienes . -3 in primary prevention of cardiovascular disease, rheumatoid arthritis and This may be important in reducing the risk of cardiovascular disease (Angerer AA can be oxidized to a variety of eicosanoid compounds important in cellcell cPLA2a may play an important role in myocardial eicosanoid . with cardiovascular disease. bogenesis as well as ischaemic heart disease and congestive

Polyunsaturated fatty acids and their effects on cardiovascular disease

9 Apr 2013 Cardiovascular disease is the leading cause of mortality in many PUFAs and their eicosanoid derivatives may play a significant role Eicosanoid biosynthesis can be initiated by release of arachidonic acid from . COX-2 may also play a role in destabilizing plaques as suggested by its increased on the molecular and cellular mechanisms underlying disease pathogenesis

Fish oils, eicosanoid biosynthesis and cardiovascular disease: an overview Evidence continues to accumulate supporting a beneficial role for fish and control of triacyglycerol biosynthesis, and thus play a key role in obesity and related disorders such as diabetes and cardiovascular disease. At the Eicosanoid